Lupien was born in Chelmsford, Massachusetts, the son of Eugenie Gosselin and Ulysses J. Lupien. His parents were of French Canadian descent, and he was named "Ulysses" because of his great-grandfather\'s admiration for president Ulysses S. Grant. He graduated from Harvard University in 1939. At Harvard, he was captain of the baseball team as a junior and of the basketball team as a senior. He was the Eastern Intercollegiate League batting champion in 1938 and 1939, and he also was a quarterback for his freshman football team.[citation needed]\n', '

Upon graduation from Harvard, Lupien signed a professional baseball contract with the Red Sox and played the 1939 season for the Double-A Scranton Red Sox Eastern League championship team. He made his major league debut for the Red Sox on September 12, 1940. One of his most productive seasons came in 1942 when he batted .281 with three home runs and 70 runs batted in for the Red Sox. He was traded to the Phillies where he played in 1944 and early in 1945, before serving in the U.S. Navy during World War II. In the 1944 season he hit .283 with five homers, 52 RBI, 82 runs, 23 doubles, 9 triples and 18 stolen bases. After his discharge from the Navy, Lupien played two years for the Hollywood Stars of the Pacific Coast League, where his 1947 record of batting .341, with 21 homers and 110 RBI, led to his return to the major leagues for one final season in 1948, with the White Sox.\n', '

Lupien finished his MLB career hitting .268 with 18 home runs, 230 RBI, 285 runs, 92 doubles, 30 triples, and 57 stolen bases in 614 games. In 1949, he played with Triple-A Toledo (American Association). He concluded his professional career from 1951–53 and in 1955 when he was a player as well as field and general manager with the Jamestown Falcons and Corning Independents, in the PONY League. From 1951 to 1956, he was head basketball coach at Middlebury College, compiling a record of 60–49 in five seasons.\n', '

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