Pollan was born on Long Island, New York, the daughter of Corinne Elaine "Corky" (Staller), a magazine editor, and Stephen Michael Pollan, a financial consultant and writer. She was raised in Woodbury, New York. Pollan is from a Russian Jewish family and was raised in the faith. She attended Syosset High School and later graduated from the Dalton School in Manhattan, New York. She studied acting at the Herbert Berghof Studio and later at the Lee Strasberg Institute.\n', '

In October 2014, Pollan, along with her two sisters and mother, co-authored The Pollan Family Table, a cookbook of family recipes, kitchen tips and cooking techniques. The foreword was written by her brother, Michael Pollan, who is the bestselling author of several books about food.\n', '

Pollan was in a five-year relationship with actor Kevin Bacon in the 1980s. She first met Michael J. Fox when she played the girlfriend of his character on Family Ties; they met again on the set of Bright Lights, Big City a couple of years later and began a relationship. They married on July 16, 1988. They have four children together: Sam Michael Fox (born May 30, 1989), twins Aquinnah Kathleen and Schuyler Frances Fox (born February 15, 1995), and Esmé Annabelle Fox (born November 3, 2001).\n', '

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