Suplee was born in Manhattan, the son of Debbie and Bill Suplee (who later played Willie the One Eyed Mailman, in My Name Is Earl). His parents were actors who met while performing summer stock and appeared on Broadway.\n', '

The first major role Suplee landed was as Willam in Mallrats, directed by Kevin Smith, alongside future My Name is Earl costar Jason Lee. He also appeared briefly in the independent Kevin Smith View-Askew produced Drawing Flies. Smith cast both Suplee and Lee again in later films Chasing Amy and Dogma. They both make cameos in Clerks II. At the same time as the filming of Mallrats, Suplee also had a recurring role as Frankie "The Enforcer" Stechino in Boy Meets World, from 1994 to 1998. Suplee\'s dramatic performances include the roles of the ruthless Nazi skinhead Seth in American History X, a man who rapes a clown in Vulgar, Ashton Kutcher\'s goth college roommate "Thumper" in The Butterfly Effect, football player Louie Lastik in 1970s Virginia in Remember the Titans (a direct opposite on his racial views from his American History X role), Johnny Depp\'s buddy and initial drug-dealing partner Tuna in Blow, and the simpleminded Pangle in Cold Mountain. Suplee also had a cameo in the HBO TV series Entourage in the fictional movie Queens Boulevard. In 2014, he was cast in the TV Land original sitcom Jennifer Falls, which reunited him with My Name Is Earl co-star, Jamie Pressly.\n', '

In 2016, Suplee started playing D in Hulu\'s series Chance, as well as police officer Billy "Beer Pong" Tompkins on the Netflix sitcom The Ranch.\n', '

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