At UFC 48, held on June 19, 2004, Dean refereed a bout between Tim Sylvia and Frank Mir for the vacant UFC Heavyweight Championship. At 0:50 (50 seconds) of round one, Dean called a stop to the fight when he saw Sylvia's right forearm break due to an armbar. Due to the close proximity of a UFC cameraman, in the video footage a shocked Dean can be heard shouting "Oh, shit!" when he saw the break, and he immediately moved in to stop the fight. This proved difficult, because Sylvia, who was still trying to defend the armbar, argued with him for several seconds, despite Dean's telling him "Stop, stop, stop! The fight is over!" Once freed from the armbar, Sylvia again began to argue with Dean, who continually told him, "It's fucking broken! Your arm is broken." Sylvia protested, claiming his arm was perfectly fine and even moving it around with no apparent problems. Dean, however, insisted that "I heard it snap. I saw it go." Ringside physician Dr. Margaret Goodman agreed with Dean's assessment, and the fight was not restarted. In the post-fight interview, Sylvia again denied that his arm was broken, however the slow-motion replay showed the break happening, and an X-ray that evening showed significant damage to Sylvia's arm, which required surgery and a long recovery. Sylvia later admitted that he knew his arm was broken and wanted to keep fighting in spite of that, but he thanked Dean for saving his career by ending the fight when he did.
At UFC 61, held on July 8, 2006, Dean served as referee of the highly anticipated rematch between Tito Ortiz and Ken Shamrock. At 1:18 into the first round, Dean stepped in and stopped the fight following several consecutive unanswered elbows to the head of Shamrock by Ortiz, giving the victory to Ortiz by TKO. Shamrock, visibly angered, immediately protested the decision. However, it was not overturned and Shamrock was subsequently ushered out of the Octagon. A rematch was held during Ortiz vs. Shamrock 3: The Final Chapter with Ortiz once again claiming victory in a very similar fashion to the second fight, although Shamrock did not question this decision.
At UFC 70, held on April 21, 2007, Dean was the referee during the bout between Mirko Cro Cop and Gabriel Gonzaga. Late in the first round, Dean stood the fight up from the guard position, a measure typically used against inactivity. Some fight analysts claim that Gonzaga was in fact administering ground and pound and had just maneuvered his opponent against the cage for an additional advantage. Shortly after the stand up, Gonzaga knocked out Filipović with a kick to the head. Filipović collapsed awkwardly after receiving the blow, pinning his right foot, which was rotated 180 degrees backwards, underneath his body. Dean quickly freed the pinned foot which helped prevent serious injury. Filipović has stated since that the elbows on the ground confused and damaged him enough that he was disoriented after the stand up, contributing to the subsequent knockout.

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