Potter was born May 10, 1990, and grew up in Southern California's Inland Empire. At birth, she was diagnosed with Down syndrome. She did not have the ability to walk until the age of 2, but then began attending dancing and acting classes at a young age. She graduated from Riverside Polytechnic High School in Riverside, California, and was studying at Irvine Valley College in Irvine, California, as of late 2011.
At the age of 16, Potter obtained her first acting role, starring in the film, Mr. Blue Sky.
From 2009 to 2015, Potter portrayed the recurring character Becky Jackson, a cheerleader with Down syndrome, in all six seasons of the TV show Glee. Cheerleading coach Sue Sylvester (Jane Lynch) takes a special interest in Becky in part because Sue's older sister, Jean, also has Down syndrome. In 2012, Potter was nominated for a SAG award in the Ensemble in a Comedy Series category for her work in Glee. She also received the SAG/AFTRA Harold Russell Award at the 2012 Media Access Awards.

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